{"id":1598,"date":"2018-05-08T09:27:26","date_gmt":"2018-05-08T07:27:26","guid":{"rendered":"https:\/\/p686699.mittwaldserver.info\/?p=1598"},"modified":"2025-03-20T09:11:32","modified_gmt":"2025-03-20T08:11:32","slug":"merging-of-several-cell-line-databases","status":"publish","type":"post","link":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/","title":{"rendered":"Merging of several cell-line databases"},"content":{"rendered":"\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>The merging of diverse databases with many hundreds of <abbr title=\"The term cell line refers to cells of a tissue type that are able to reproduce indefinitely in a cell culture outside the organism.\">cell lines<\/abbr> used in medical research necessitated the review and verification of the information stored in them.<\/p>\n<\/blockquote>\n\n\n\n<p><strong>Project duration:<\/strong> 3 months<br><br>For a leading pharmaceutical company, we checked many hundreds of data records for correctness and supplemented missing information. Every data record characterized a <abbr title=\"The term cell line refers to cells of a tissue type that are able to reproduce indefinitely in a cell culture outside the organism.\">cell line<\/abbr> used in medical research. Verification of data was necessary in this case, as data records from several independent databases were aggregated, which led to content inconsistencies. We reviewed the correct designation of the cell line and corresponding synonyms, species and gender of the cells, tissue or organ of collected samples, and the age of the donor organism and, if necessary, the underlying disease. The substantial expertise of the biologists at GIMD was invaluable in this. In some cases, allocations proved to be unambiguous. In others, incorrectly allocated and much conflicting information on individual parameters had to be harmonized and given uniform descriptions according to the cell line in question. Processing was performed predominately as Internet research, within a time frame prescribed by the budgeting of the client. Clearly incorrect allocations were removed, and verified data was marked as such. In addition, unresolvable contradictions (e.g. contaminations of formerly established cell lines known from the literature) and possibilities of confusion (e.g. identical designations for cell lines of different species or cell lines which had been erroneously assigned to the wrong species over the course of research) were pointed out. After data synchronization and post-processing, the data records were submitted to the client in the digital format requested.<br><br>This project once again proves GIMD\u2019s great flexibility in the processing (analysis, documentation, conversion) of data (records) from the most diverse fields.<\/p>\n\n\n\n<p class=\"has-text-align-right\"><a href=\"https:\/\/gimd.de\/en\/contact\/\">Contact<\/a> <a href=\"https:\/\/gimd.de\/en\/category\/projects\/#projectsContent\">Show all<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The merging of diverse databases with many hundreds of cell lines used in medical research necessitated the review and verification [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[93,78,118,71,108,105],"tags":[],"class_list":["post-1598","post","type-post","status-publish","format-standard","hentry","category-databases","category-life-science-en","category-processing-editing","category-projects","category-researching","category-structuring"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Merging of several cell-line databases &#8211; GIMD<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Merging of several cell-line databases &#8211; GIMD\" \/>\n<meta property=\"og:description\" content=\"The merging of diverse databases with many hundreds of cell lines used in medical research necessitated the review and verification [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/\" \/>\n<meta property=\"og:site_name\" content=\"GIMD\" \/>\n<meta property=\"article:published_time\" content=\"2018-05-08T07:27:26+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-20T08:11:32+00:00\" \/>\n<meta name=\"author\" content=\"gimd-redaktion\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"gimd-redaktion\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/\"},\"author\":{\"name\":\"gimd-redaktion\",\"@id\":\"https:\/\/gimd.de\/en\/#\/schema\/person\/ba78560ef83b195d9b67f42a1c6e0a6e\"},\"headline\":\"Merging of several cell-line databases\",\"datePublished\":\"2018-05-08T07:27:26+00:00\",\"dateModified\":\"2025-03-20T08:11:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/\"},\"wordCount\":292,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/gimd.de\/en\/#organization\"},\"articleSection\":[\"Databases\",\"Life Science\",\"processing\/editing\",\"Projects\",\"researching\",\"structuring\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/\",\"url\":\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/\",\"name\":\"Merging of several cell-line databases &#8211; GIMD\",\"isPartOf\":{\"@id\":\"https:\/\/gimd.de\/en\/#website\"},\"datePublished\":\"2018-05-08T07:27:26+00:00\",\"dateModified\":\"2025-03-20T08:11:32+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\/\/gimd.de\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Merging of several cell-line databases\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/gimd.de\/en\/#website\",\"url\":\"https:\/\/gimd.de\/en\/\",\"name\":\"GIMD\",\"description\":\"Limited Corporation for Information Management and Documentation\",\"publisher\":{\"@id\":\"https:\/\/gimd.de\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/gimd.de\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/gimd.de\/en\/#organization\",\"name\":\"Gesellschaft f\u00fcr Informations-Management und Dokumentation mbH\",\"url\":\"https:\/\/gimd.de\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/gimd.de\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/gimd.de\/wp-content\/uploads\/2025\/03\/cropped-GIMD-Logo-002.png\",\"contentUrl\":\"https:\/\/gimd.de\/wp-content\/uploads\/2025\/03\/cropped-GIMD-Logo-002.png\",\"width\":800,\"height\":140,\"caption\":\"Gesellschaft f\u00fcr Informations-Management und Dokumentation mbH\"},\"image\":{\"@id\":\"https:\/\/gimd.de\/en\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/gimd.de\/en\/#\/schema\/person\/ba78560ef83b195d9b67f42a1c6e0a6e\",\"name\":\"gimd-redaktion\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/secure.gravatar.com\/avatar\/e0982fccb74046b96083b824011f76dd98b3644c85bed7cc8c056ebb40fcb2cd?s=96&d=mm&r=g\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/e0982fccb74046b96083b824011f76dd98b3644c85bed7cc8c056ebb40fcb2cd?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/e0982fccb74046b96083b824011f76dd98b3644c85bed7cc8c056ebb40fcb2cd?s=96&d=mm&r=g\",\"caption\":\"gimd-redaktion\"},\"url\":\"https:\/\/gimd.de\/en\/author\/gimd-redaktion\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Merging of several cell-line databases &#8211; GIMD","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/","og_locale":"en_US","og_type":"article","og_title":"Merging of several cell-line databases &#8211; GIMD","og_description":"The merging of diverse databases with many hundreds of cell lines used in medical research necessitated the review and verification [&hellip;]","og_url":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/","og_site_name":"GIMD","article_published_time":"2018-05-08T07:27:26+00:00","article_modified_time":"2025-03-20T08:11:32+00:00","author":"gimd-redaktion","twitter_card":"summary_large_image","twitter_misc":{"Written by":"gimd-redaktion","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/#article","isPartOf":{"@id":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/"},"author":{"name":"gimd-redaktion","@id":"https:\/\/gimd.de\/en\/#\/schema\/person\/ba78560ef83b195d9b67f42a1c6e0a6e"},"headline":"Merging of several cell-line databases","datePublished":"2018-05-08T07:27:26+00:00","dateModified":"2025-03-20T08:11:32+00:00","mainEntityOfPage":{"@id":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/"},"wordCount":292,"commentCount":0,"publisher":{"@id":"https:\/\/gimd.de\/en\/#organization"},"articleSection":["Databases","Life Science","processing\/editing","Projects","researching","structuring"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/","url":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/","name":"Merging of several cell-line databases &#8211; GIMD","isPartOf":{"@id":"https:\/\/gimd.de\/en\/#website"},"datePublished":"2018-05-08T07:27:26+00:00","dateModified":"2025-03-20T08:11:32+00:00","breadcrumb":{"@id":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/gimd.de\/en\/2018\/05\/08\/merging-of-several-cell-line-databases\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/gimd.de\/en\/"},{"@type":"ListItem","position":2,"name":"Merging of several cell-line databases"}]},{"@type":"WebSite","@id":"https:\/\/gimd.de\/en\/#website","url":"https:\/\/gimd.de\/en\/","name":"GIMD","description":"Limited Corporation for Information Management and Documentation","publisher":{"@id":"https:\/\/gimd.de\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/gimd.de\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/gimd.de\/en\/#organization","name":"Gesellschaft f\u00fcr Informations-Management und Dokumentation mbH","url":"https:\/\/gimd.de\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/gimd.de\/en\/#\/schema\/logo\/image\/","url":"https:\/\/gimd.de\/wp-content\/uploads\/2025\/03\/cropped-GIMD-Logo-002.png","contentUrl":"https:\/\/gimd.de\/wp-content\/uploads\/2025\/03\/cropped-GIMD-Logo-002.png","width":800,"height":140,"caption":"Gesellschaft f\u00fcr Informations-Management und Dokumentation mbH"},"image":{"@id":"https:\/\/gimd.de\/en\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/gimd.de\/en\/#\/schema\/person\/ba78560ef83b195d9b67f42a1c6e0a6e","name":"gimd-redaktion","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/e0982fccb74046b96083b824011f76dd98b3644c85bed7cc8c056ebb40fcb2cd?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/e0982fccb74046b96083b824011f76dd98b3644c85bed7cc8c056ebb40fcb2cd?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/e0982fccb74046b96083b824011f76dd98b3644c85bed7cc8c056ebb40fcb2cd?s=96&d=mm&r=g","caption":"gimd-redaktion"},"url":"https:\/\/gimd.de\/en\/author\/gimd-redaktion\/"}]}},"_links":{"self":[{"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/posts\/1598","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/comments?post=1598"}],"version-history":[{"count":3,"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/posts\/1598\/revisions"}],"predecessor-version":[{"id":1605,"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/posts\/1598\/revisions\/1605"}],"wp:attachment":[{"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/media?parent=1598"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/categories?post=1598"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gimd.de\/en\/wp-json\/wp\/v2\/tags?post=1598"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}